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欧盟评估扩展使用非转基因黑曲霉菌株294生产的纤维素酶的安全性

放大字体  缩小字体 时间:2026-07-16 16:28 来源:食品伙伴网 作者:泽夕  
核心提示:2026年7月10日,欧盟食品安全局就一种食品酶纤维素酶(cellulase)的安全性评价发布意见。
   食品伙伴网讯  2026年7月10日,欧盟食品安全局就一种食品酶纤维素酶(cellulase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因黑曲霉菌株294生产的,旨在用于11种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme cellulase (4-(1,3;1,4)-β-D-glucan-4-glucanohydrolase; EC 3.2.1.4) is produced with the non-genetically modified Aspergillus niger strain 294 by Kerry Ingredients & Flavours Ltd. The safety of this food enzyme was evaluated previously, and it did not give rise to safety concerns when used in eight food manufacturing processes for adolescents, adults and the elderly. Subsequently, the applicant has requested to extend its use to include three additional processes and to revise the use levels. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of eleven food manufacturing processes. As the food enzyme–Total Organic Solids (TOS) are removed in two food manufacturing processes, the dietary exposure to the food enzyme–TOS was estimated for the remaining nine processes. It was estimated to be up to 2.998 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (794 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 265 for all age groups. based on the revised exposure estimation, the newly derived margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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