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欧盟评估扩展使用转基因黑曲霉菌株NZYM-FP生产的磷脂酶A1的安全性

放大字体  缩小字体 时间:2026-07-22 11:12 来源:食品伙伴网 作者:泽夕  
核心提示:2026年7月15日,欧盟食品安全局就一种食品酶磷脂酶A1(phospholipase A1)的安全性评价发布意见。
   食品伙伴网讯  2026年7月15日,欧盟食品安全局就一种食品酶磷脂酶A1(phospholipase A1)的安全性评价发布意见。
 
  据了解,这种食品酶是由转基因黑曲霉菌株NZYM-FP生产的,旨在用于5种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme phospholipase A1 (phosphatidylcholine 1-acylhydrolase, EC 3.1.1.32) is produced with the genetically modified Aspergillus niger strain NZYM-FP by Novozymes A/S. The safety of this food enzyme was evaluated previously, and it did not give rise to safety concerns when used in one food manufacturing process. Subsequently, the applicant has requested to extend its use to include four additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of five food manufacturing processes. As the food enzyme-Total Organic Solids (TOS) are removed in one process, the dietary exposure to the food enzyme-TOS was estimated for the remaining four food manufacturing processes. It was calculated to be up to 0.406 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1356 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 3339. based on the revised exposure estimation, the newly derived margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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